Police were reported by the AP on Sunday as saying the women apparently suffered gunshot wounds, but investigators haven't released the cause of death.
Police know of no possible suspects at this time.
North Royalton police said the victims were Taylor Pifer, 21, Kylie Pifer, 18, and their mother Suzanne Taylor, 45.
A section of Valley Forge Drive was blocked off by police, but a crowd of about two-dozen onlookers gathered across the street around midnight to watch the situation. When police arrived a woman was seen emerging from the house.
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The U.S. statement of solidarity with the attack's victims is notable because of the deep distrust between the U.S. and Iran. The IS media arm Aamaq released a video Thursday evening showing what it claimed was a message from the Tehran attackers.
Police said the three women may have died the day before their bodies were found. He said he called Taylor's boyfriend, Scott Plymale, who then called 911.
Suzanne's boyfriend also tells the 911 dispatcher that he delivered flowers to the house on Saturday but did not see anyone inside, .
A motive for the killings remains unclear, but police said the case does not involve a suicide.
So far, no arrests have been made.
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A report via Fox8 told of Taylor studying fashion design at Kent State University and playing softball.
The 21-year-old wrote in the bio on her Facebook page: 'Life's too short to sit and wait for luck to come your way'.
Taylor was the mother of the Pifer girls, both of whom had been estranged from their biological father for at least a year. Taylor was a student at Kent State University in Kent, Ohio, while Kylie attended Bowling Green University.
Kylie was due to celebrate her 19th birthday on June 11, according to WEWS.
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Iranian Foreign Minister Mohammad Javad-Zarif called it "repugnant" on Twitter and said the Iranian people "reject" the statement. The U.S. statement of solidarity with the attack's victims is notable because of the deep distrust between the U.S. and Iran.
Told Pifer, 'They were great kids... and this totally, totally blind-sided us'. "I can not tell you on the others because there's not a visible sign of how death occurred", said North Royalton Det.